The Division of Experimental Medicine (DEM) is a new research unit that was established within the UCSF Department of Medicine in 2006 to create a multidisciplinary team of investigators focused on the human immunology of chronic infectious diseases. The DEM has since grown rapidly to encompass 7 faculty members and their research laboratories, as well as a Core Immunology Laboratory. Together the scientific and administrative staff of the DEM has expanded to include 85 individuals.

The work of the DEM encompasses studies carried out in our 20,000 sq. ft. facility at San Francisco General Hospital as well as at multiple clinical studies in San Francisco and around the world (e.g., Brazil, Uganda, Zimbabwe, Namibia, Tanzania, Swaziland, Australia, Sweden, England, and France). Most of these studies are conducted in close collaboration with basic research scientists and clinical investigators from other divisions and departments at UCSF and with other collaborating institutions. In aggregate, the DEM has quickly become a .virtual. environment, unconstrained by physical walls, in which it is possible to study multiple chronic infectious agents simultaneously in the context of a value system that embraces and rewards multidisciplinary collaboration. The DEM has developed a unique and potentially transformative process for understanding host-pathogen interactions in humans, for deciphering which human immune responses might best protect against the acquisition of such agents, and . ultimately . for informing, testing, and implementing the development of novel vaccines for widespread distribution.