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Virology
A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads.
Evolution of coreceptor utilization to escape CCR5 antagonist therapy.
Efficacy of broadly neutralizing monoclonal antibody PG16 in HIV-infected humanized mice.
Heat shock protein 90AB1 and hyperthermia rescue infectivity of HIV with defective cores.
Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2R?(-/-) (NSG) BLT mice.
Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.
Identification of HIV-1 determinants for replication in vivo.
Murine cytomegalovirus IE2, an activator of gene expression, is dispensable for growth and latency in mice.
