Mary Prahl, MD

Education
2019 - Diversity, Equity, and Inclusion Champion Training, University of California
Fellowship, 2016 - Pediatric Infectious Disease, UCSF
Residency, 2012 - Pediatrics, Northwestern/Ann and Robert H. Lurie Children's Hospital of Chicago
M.D., 2009 - Medicine, University of Minnesota
B.S., 2004 - Biochemistry, College of Saint Scholastica
Honors and Awards
  • LRP Award, NIH, 2017-2022
  • Melvin M. Grumbach Award for Excellence in Research, UCSF, 2017
  • Merle A. Sande/Pfizer Fellowship Award in International Infectious Diseases, IDSA Foundation, 2014
  • Research Scholars Day Judges' Award, Northwestern University, 2012
  • Alpha Omega Alpha Honor Medical Society, Northwestern University, 2011
  • Resident Teaching Award, Children's Memorial Hospital/Northwestern University, 2009
  • Summa Cum Laude, College of Saint Scholastica, 2004
Websites
Publications
  1. Jaswa EG, Cedars MI, Lindquist KJ, Bishop SL, Kim YS, Kaing A, Prahl M, Gaw SL, Corley J, Hoskin E, Cho YJ, Rogers E, Huddleston HG. In Utero Exposure to Maternal COVID-19 Vaccination and Offspring Neurodevelopment at 12 and 18 Months. JAMA pediatrics 2024. PMID: 38252445


  2. Golan Y, Ilala M, Li L, Gay C, Hunagund S, Lin CY, Cassidy AG, Jigmeddagva U, Matsui Y, Ozarslan N, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL, Prahl M. Milk antibody response after 3rd COVID-19 vaccine and SARS-CoV-2 infection and implications for infant protection. iScience 2023. PMID: 37731614


  3. Gonzalez VJ, Li L, Buarpung S, Prahl M, Robinson JF, Gaw SL. Minimal mRNA uptake and inflammatory response to COVID-19 mRNA vaccine exposure in human placental explants. iScience 2023. PMID: 37664582


  4. Cassidy AG, Li L, Golan Y, Gay C, Lin CY, Jigmeddagva U, Chidboy MA, Ilala M, Buarpung S, Gonzalez VJ, Basilio E, Duck M, Murtha AP, Wu AHB, Lynch KL, Asiodu IV, Prahl MK, Gaw SL. Assessment of Adverse Reactions, Antibody Patterns, and 12-month Outcomes in the Mother-Infant Dyad After COVID-19 mRNA Vaccination in Pregnancy. JAMA network open 2023. PMID: 37450302


  5. Lin CY, Cassidy AG, Li L, Prahl MK, Golan Y, Gaw SL. Nirmatrelvir-Ritonavir (Paxlovid) for Mild Coronavirus Disease 2019 (COVID-19) in Pregnancy and Lactation. Obstetrics and gynecology 2023. PMID: 36928334


  6. Gonzalez V, Li L, Buarpung S, Prahl M, Robinson JF, Gaw SL. Minimal mRNA uptake and inflammatory response to COVID-19 mRNA vaccine exposure in human placental explants. medRxiv : the preprint server for health sciences 2023. PMID: 36778281


  7. Golan Y, Ilala M, Gay C, Hunagund S, Lin CY, Cassidy AG, Jigmeddagva U, Li L, Ozarslan N, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL, Prahl M. Milk antibody response after 3rd dose of COVID-19 mRNA vaccine and SARS-CoV-2 breakthrough infection and implications for infant protection. medRxiv : the preprint server for health sciences 2022. PMID: 36561188


  8. Vaaben AV, Levan J, Nguyen CBT, Callaway PC, Prahl M, Warrier L, Nankya F, Musinguzi K, Kakuru A, Muhindo MK, Dorsey G, Kamya MR, Feeney ME. In Utero Activation of NK Cells in Congenital CMV Infection. The Journal of infectious diseases 2022. PMID: 35876164


  9. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy. Nature communications 2022. PMID: 35908075


  10. Hunagund S, Golan Y, Asiodu IV, Prahl M, Gaw SL. Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity. Frontiers in Immunology 2022. PMID: 35903100


  11. Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens JM, Rincon M, Myatt L, Asiodu IV, Flaherman VJ, Afshar Y, Jacoby VL, Murtha AP, Robinson JF, Ott M, Greene WC, Gaw SL. Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination. A Phenomenological Study of Lesbian and Gay People in Leadership Roles: How Perspectives and Priorities Shift in the Workplace a Sexual Orientation Evolves through Social Constructs (Doctoral dissertation) 2022. PMID: 35579965


  12. Chakraborty S, Gonzalez JC, Sievers BL, Mallajosyula V, Chakraborty S, Dubey M, Ashraf U, Cheng BY, Kathale N, Tran KQT, Scallan C, Sinnott A, Cassidy A, Chen ST, Gelbart T, Gao F, Golan Y, Ji X, Kim-Schulze S, Prahl M, Gaw SL, Gnjatic S, Marron TU, Merad M, Arunachalam PS, Boyd SD, Davis MM, Holubar M, Khosla C, Maecker HT, Maldonado Y, Mellins ED, Nadeau KC, Pulendran B, Singh U, Subramanian A, Utz PJ, Sherwood R, Zhang S, Jagannathan P, Tan GS, Wang TT. Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity. A Phenomenological Study of Lesbian and Gay People in Leadership Roles: How Perspectives and Priorities Shift in the Workplace a Sexual Orientation Evolves through Social Constructs (Doctoral dissertation) 2022. PMID: 35040666


  13. Sievers BL, Chakraborty S, Xue Y, Gelbart T, Gonzalez JC, Cassidy AG, Golan Y, Prahl M, Gaw SL, Arunachalam PS, Blish CA, Boyd SD, Davis MM, Jagannathan P, Nadeau KC, Pulendran B, Singh U, Scheuermann RH, Frieman MB, Vashee S, Wang TT, Tan GS. Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses. A Phenomenological Study of Lesbian and Gay People in Leadership Roles: How Perspectives and Priorities Shift in the Workplace a Sexual Orientation Evolves through Social Constructs (Doctoral dissertation) 2022. PMID: 35025672


  14. Chakraborty S, Gonzalez JC, Sievers BL, Mallajosyula V, Dubey M, Cheng BY, Thi Tran KQ, Chakraborty S, Cassidy A, Chen ST, Sinnott A, Gelbart T, Golan Y, Prahl M, Singh U, Kim-Schulze S, Sherwood R, Zhang S, Marron TU, Gnjatic S, Gaw SL, Nadeau KC, Merad M, Jagannathan P, Tan GS, Wang TT. Divergent early antibody responses define COVID-19 disease trajectories. bioRxiv : the preprint server for biology 2021. PMID: 34075376


  15. Prahl M, Golan Y, Cassidy A, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin C, Gonzalez V, Chidboy M, Warrier L, Buarpung S, Murtha A, Flaherman V, Greene W, Wu A, Lynch K, Rajan J, Gaw S. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. A Phenomenological Study of Lesbian and Gay People in Leadership Roles: How Perspectives and Priorities Shift in the Workplace a Sexual Orientation Evolves through Social Constructs (Doctoral dissertation) 2021. PMID: 34931183


  16. Simon N, Shallat J, Houck J, Jagannathan P, Prahl M, Muhindo MK, Kakuru A, Olwoch P, Feeney ME, Harrington WE. Peripheral Plasmodium falciparum infection in early pregnancy is associated with increased maternal microchimerism in the offspring. The Journal of infectious diseases 2021. PMID: 34010401


  17. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. A Phenomenological Study of Lesbian and Gay People in Leadership Roles: How Perspectives and Priorities Shift in the Workplace a Sexual Orientation Evolves through Social Constructs (Doctoral dissertation) 2021. PMID: 34931197


  18. Golan Y, Prahl M, Cassidy AG, Gay C, Wu AHB, Jigmeddagva U, Lin CY, Gonzalez VJ, Basilio E, Chidboy MA, Warrier L, Buarpung S, Li L, Murtha AP, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL. COVID-19 mRNA Vaccination in Lactation: Assessment of Adverse Events and Vaccine Related Antibodies in Mother-Infant Dyads. A Phenomenological Study of Lesbian and Gay People in Leadership Roles: How Perspectives and Priorities Shift in the Workplace a Sexual Orientation Evolves through Social Constructs (Doctoral dissertation) 2021. PMID: 34804068


  19. Flaherman VJ, Afshar Y, Boscardin J, Keller RL, Mardy A, Prahl MK, Phillips C, Asiodu IV, Berghella WV, Chambers BD, Crear-Perry J, Jamieson DJ, Jacoby VL, Gaw SL. Infant Outcomes Following Maternal Infection with SARS-CoV-2: First Report from the PRIORITY Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020. PMID: 32947612


  20. Golan Y, Prahl M, Cassidy A, Lin CY, Ahituv N, Flaherman VJ, Gaw SL. Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk. JAMA pediatrics 2021. PMID: 34228115


  21. Golan Y, Prahl M, Cassidy AG, Gay C, Wu AHB, Jigmeddagva U, Lin CY, Gonzalez VJ, Basilio E, Warrier L, Buarpung S, Li L, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL. COVID-19 mRNA Vaccination in Lactation: Assessment of adverse effects and transfer of anti-SARS-CoV2 antibodies from mother to child. medRxiv : the preprint server for health sciences 2021. PMID: 34373861


  22. Song D, Prahl M, Gaw SL, Narasimhan SR, Rai DS, Huang A, Flores CV, Lin CY, Jigmeddagva U, Wu A, Warrier L, Levan J, Nguyen CBT, Callaway P, Farrington L, Acevedo GR, Gonzalez VJ, Vaaben A, Nguyen P, Atmosfera E, Marleau C, Anderson C, Misra S, Stemmle M, Cortes M, McAuley J, Metz N, Patel R, Nudelman M, Abraham S, Byrne J, Jegatheesan P. Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: prospective cohort study. BMJ open 2021. PMID: 34234001


  23. Song D, Prahl M, Gaw SL, Narasimhan S, Rai D, Huang A, Flores C, Lin CY, Jigmeddagva U, Wu AHB, Warrier L, Levan J, Nguyen CBT, Callaway P, Farrington L, Acevedo GR, Gonzalez VJ, Vaaben A, Nguyen P, Atmosfera E, Marleau C, Anderson C, Misra S, Stemmle M, Cortes M, McAuley J, Metz N, Patel R, Nudelman M, Abraham S, Byrne J, Jegatheesan P. Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: Prospective cohort study. medRxiv : the preprint server for health sciences 2021. PMID: 33972953


  24. Prahl M, Odorizzi P, Gingrich D, Muhindo M, McIntyre T, Budker R, Jagannathan P, Farrington L, Nalubega M, Nankya F, Sikyomu E, Musinguzi K, Naluwu K, Auma A, Kakuru A, Kamya MR, Dorsey G, Aweeka F, Feeney ME. Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy. Nature communications 2021. PMID: 33420104


  25. Blauvelt CA, Chiu C, Donovan AL, Prahl M, Shimotake TK, George RB, Schwartz BS, Farooqi NA, Ali SS, Cassidy A, Gonzalez JM, Gaw SL. Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19). Obstetrics and gynecology 2020. PMID: 32384385


  26. Odorizzi PM, Jagannathan P, McIntyre TI, Budker R, Prahl M, Auma A, Burt TD, Nankya F, Nalubega M, Sikyomu E, Musinguzi K, Naluwu K, Kakuru A, Dorsey G, Kamya MR, Feeney ME. In utero priming of highly functional effector T cell responses to human malaria. Science translational medicine 2018. PMID: 30333241


  27. Jagannathan P, Kakuru A, Okiring J, Muhindo MK, Natureeba P, Nakalembe M, Opira B, Olwoch P, Nankya F, Ssewanyana I, Tetteh K, Drakeley C, Beeson J, Reiling L, Clark TD, Rodriguez-Barraquer I, Greenhouse B, Wallender E, Aweeka F, Prahl M, Charlebois ED, Feeney ME, Havlir DV, Kamya MR, Dorsey G. Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial. PLoS medicine 2018. PMID: 30016328


  28. Farrington L, Vance H, Rek J, Prahl M, Jagannathan P, Katureebe A, Arinaitwe E, Kamya MR, Dorsey G, Feeney ME. Both inflammatory and regulatory cytokine responses to malaria are blunted with increasing age in highly exposed children. Malaria journal 2017. PMID: 29284469


  29. Prahl M, Jagannathan P, McIntyre TI, Auma A, Wamala S, Nalubega M, Musinguzi K, Naluwu K, Sikyoma E, Budker R, Odorizzi P, Kakuru A, Havlir DV, Kamya MR, Dorsey G, Feeney ME. Sex Disparity in Cord Blood FoxP3+ CD4 T Regulatory Cells in Infants Exposed to Malaria In Utero. Open forum infectious diseases 2017. PMID: 28480292


  30. Prahl M, Jagannathan P, McIntyre TI, Auma A, Farrington L, Wamala S, Nalubega M, Musinguzi K, Naluwu K, Sikyoma E, Budker R, Vance H, Odorizzi P, Nayebare P, Ategeka J, Kakuru A, Havlir DV, Kamya MR, Dorsey G, Feeney ME. Timing of in utero malaria exposure influences fetal CD4 T cell regulatory versus effector differentiation. Malaria journal 2016. PMID: 27717402


  31. Prahl M, Dhaliwal G, Shulman ST, Doshi N, Monash B. Another spin. Journal of hospital medicine 2016. PMID: 27018991


  32. Prahl M, Smetana D, Porta N. Lactobezoar formation in two premature infants receiving medium-chain triglyceride formula. Journal of perinatology : official journal of the California Perinatal Association 2014. PMID: 25073493