Weihao Zheng, PhD

Postdoctoral Scholar

Weihao (he/him/his) grew up in Eastern Guangdong of China, and attended South China University of Technology for his undergraduate degree in Guangzhou. He completed his PhD degree in Dr. Zigang Li’s lab at Peking university, where he focused on structural, functional and inhibitor studies of Ser/Thr kinase/phosphatase Stk1/Stp1 from S. aureus, and was involved in the development of a new hepatitis B virus (HBV) vaccine and HBV peptide inhibitors. As a postdoc in Ernst lab, he is studying mechanisms of immune evasion by Mtb.

When not in the lab, Weihao loves playing basketball, cooking, and swimming.
Publications
  1. Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, Brodsky E, Rousseau E, Capponi S, Bianco S, Nakamura R, Jackson PK, Frydman J, Andino R. A defective viral genome strategy elicits broad protective immunity against respiratory viruses. 2021. PMID: 34852237


  2. Hiatt J, Cavero DA, McGregor MJ, Zheng W, Budzik JM, Roth TL, Haas KM, Wu D, Rathore U, Meyer-Franke A, Bouzidi MS, Shifrut E, Lee Y, Kumar VE, Dang EV, Gordon DE, Wojcechowskyj JA, Hultquist JF, Fontaine KA, Pillai SK, Cox JS, Ernst JD, Krogan NJ, Marson A. Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins. 2021. PMID: 33979618


  3. Cai X, Zheng W, Shi X, Chen L, Liu Z, Li Z. HBx-Derived Constrained Peptides Inhibit the Secretion of Hepatitis B Virus Antigens. 2018. PMID: 30375875


  4. Jiang Y, Deng Q, Zhao H, Xie M, Chen L, Yin F, Qin X, Zheng W, Zhao Y, Li Z. Development of Stabilized Peptide-Based PROTACs against Estrogen Receptor a. 2018. PMID: 29271628


  5. Cai X, Zheng W, Pan S, Zhang S, Xie Y, Guo H, Wang G, Li Z, Luo M. A virus-like particle of the hepatitis B virus preS antigen elicits robust neutralizing antibodies and T cell responses in mice. 2017. PMID: 29129705


  6. Zhao H, Qin X, Yang D, Jiang Y, Zheng W, Wang D, Tian Y, Liu Q, Xu N, Li Z. The development of activatable lytic peptides for targeting triple negative breast cancer. 2017. PMID: 29263848


  7. Zheng WH, Lin ZQ, Zhuo M, Du HL, Wang XN. [Research progress on influenza antiviral small RNAs]. 2012. PMID: 22659424


  8. Du H, Hu H, Meng Y, Zheng W, Ling F, Wang J, Zhang X, Nie Q, Wang X. The correlation coefficient of GC content of the genome-wide genes is positively correlated with animal evolutionary relationships. 2010. PMID: 20691688